Co-culture of primary CLL cells with bone marrow mesenchymal cells, CD40 ligand and CpG ODN promotes proliferation of chemoresistant CLL cells phenotypically comparable to those proliferating in vivo

Chronic lymphocytic leukemia (CLL) cells residing in the bone marrow (BM) and in secondary lymphoid tissues receive survival and proliferative signals from the microenvironment, resulting in persistence of residual disease after treatment. In this study, we characterized primary CLL cells cultured w...

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Detalles Bibliográficos
Autores principales: Purroy, Noelia, Abrisqueta, Pau, Carabia, Júlia, Carpio, Cecilia, Palacio, Carles, Bosch, Francesc, Crespo, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480705/
https://www.ncbi.nlm.nih.gov/pubmed/25544766

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