Loss of miR-200c up-regulates CYP1B1 and confers docetaxel resistance in renal cell carcinoma

Despite high protein expression and enzymatic activity of cytochrome P450 1B1 (CYP1B1) in renal cell cancer (RCC), its functional significance has not been elucidated. Here we explored the functional role and regulatory mechanism of CYP1B1 in RCC. Reduction of CYP1B1 levels fail to prevent in vitro...

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Detalles Bibliográficos
Autores principales: Chang, Inik, Mitsui, Yozo, Fukuhara, Shinichiro, Gill, Ankurpreet, Wong, Darryn K., Yamamura, Soichiro, Shahryari, Varahram, Tabatabai, Z. Laura, Dahiya, Rajvir, Shin, Dong Min, Tanaka, Yuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480715/
https://www.ncbi.nlm.nih.gov/pubmed/25860934

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