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UV irradiation/cold shock-mediated apoptosis is switched to bubbling cell death at low temperatures
When COS7 fibroblasts and other cells were exposed to UVC irradiation and cold shock at 4°C for 5 min, rapid upregulation and nuclear accumulation of NOS2, p53, WWOX, and TRAF2 occurred in 10–30 min. By time-lapse microscopy, an enlarging gas bubble containing nitric oxide (NO) was formed in the nuc...
Autores principales: | Chen, Szu-Jung, Lin, Pei-Wen, Lin, Hsin-Ping, Huang, Shenq-Shyang, Lai, Feng-Jie, Sheu, Hamm-Ming, Hsu, Li-Jin, Chang, Nan-Shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480731/ https://www.ncbi.nlm.nih.gov/pubmed/25779665 |
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