Systems biology network-based discovery of a small molecule activator BL-AD008 targeting AMPK/ZIPK and inducing apoptosis in cervical cancer

The aim of this study was to discover a small molecule activator BL-AD008 targeting AMPK/ZIPK and inducing apoptosis in cervical cancer. In this study, we systematically constructed the global protein-protein interaction (PPI) network and predicted apoptosis-related protein connections by the Naïve...

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Detalles Bibliográficos
Autores principales: Fu, Leilei, Zhang, Shouyue, Zhang, Lan, Tong, Xupeng, Zhang, Jin, Zhang, Yonghui, Ouyang, Liang, Liu, Bo, Huang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480736/
https://www.ncbi.nlm.nih.gov/pubmed/25797270

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