Peripheral myeloid-derived suppressor and T regulatory PD-1 positive cells predict response to neoadjuvant short-course radiotherapy in rectal cancer patients

Short-course preoperative radiotherapy (SC-RT) followed by total mesorectal excision (TME) is one therapeutic option for locally advanced rectal cancer (LARC) patients. Since radio-induced DNA damage may affect tumor immunogenicity, Myeloid-derived suppressor cells (MDSCs) and T regulatory cells (Tr...

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Detalles Bibliográficos
Autores principales: Napolitano, Maria, D'Alterio, Crescenzo, Cardone, Eleonora, Trotta, Anna Maria, Pecori, Biagio, Rega, Daniela, Pace, Ugo, Scala, Dario, Scognamiglio, Giosuè, Tatangelo, Fabiana, Cacciapuoti, Carmela, Pacelli, Roberto, Delrio, Paolo, Scala, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480750/
https://www.ncbi.nlm.nih.gov/pubmed/25823653

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