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Mitochondrial Morphology and Fundamental Parameters of the Mitochondrial Respiratory Chain Are Altered in Caenorhabditis elegans Strains Deficient in Mitochondrial Dynamics and Homeostasis Processes

Mitochondrial dysfunction has been linked to myriad human diseases and toxicant exposures, highlighting the need for assays capable of rapidly assessing mitochondrial health in vivo. Here, using the Seahorse XF(e)24 Analyzer and the pharmacological inhibitors dicyclohexylcarbodiimide and oligomycin...

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Detalles Bibliográficos
Autores principales:	Luz, Anthony L., Rooney, John P., Kubik, Laura L., Gonzalez, Claudia P., Song, Dong Hoon, Meyer, Joel N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480853/ https://www.ncbi.nlm.nih.gov/pubmed/26106885 http://dx.doi.org/10.1371/journal.pone.0130940

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