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Enediynes: Exploration of microbial genomics to discover new anticancer drug leads

The enediyne natural products have been explored for their phenomenal cytotoxicity. The development of enediynes into anticancer drugs has been successfully achieved through the utilization of polymer- and antibody–drug conjugates (ADCs) as drug delivery systems. An increasing inventory of enediynes...

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Detalles Bibliográficos
Autores principales:	Shen, Ben, Hindra, Yan, Xiaohui, Huang, Tingting, Ge, Huiming, Yang, Dong, Teng, Qihui, Rudolf, Jeffrey D., Lohman, Jeremy R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480864/ https://www.ncbi.nlm.nih.gov/pubmed/25434000 http://dx.doi.org/10.1016/j.bmcl.2014.11.019

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