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Bioinformatics analysis of thousands of TCGA tumors to determine the involvement of epigenetic regulators in human cancer
BACKGROUND: Many cancer cells show distorted epigenetic landscapes. The Cancer Genome Atlas (TCGA) project profiles thousands of tumors, allowing the discovery of somatic alterations in the epigenetic machinery and the identification of potential cancer drivers among members of epigenetic protein fa...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480953/ https://www.ncbi.nlm.nih.gov/pubmed/26110843 http://dx.doi.org/10.1186/1471-2164-16-S8-S5 |