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Bioinformatics analysis of thousands of TCGA tumors to determine the involvement of epigenetic regulators in human cancer

BACKGROUND: Many cancer cells show distorted epigenetic landscapes. The Cancer Genome Atlas (TCGA) project profiles thousands of tumors, allowing the discovery of somatic alterations in the epigenetic machinery and the identification of potential cancer drivers among members of epigenetic protein fa...

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Detalles Bibliográficos
Autores principales: Gnad, Florian, Doll, Sophia, Manning, Gerard, Arnott, David, Zhang, Zemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480953/
https://www.ncbi.nlm.nih.gov/pubmed/26110843
http://dx.doi.org/10.1186/1471-2164-16-S8-S5