Insights from GWAS: emerging landscape of mechanisms underlying complex trait disease

BACKGROUND: There are now over 2000 loci in the human genome where genome wide association studies (GWAS) have found one or more SNPs to be associated with altered risk of a complex trait disease. At each of these loci, there must be some molecular level mechanism relevant to the disease. What are t...

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Detalles Bibliográficos
Autores principales: Pal, Lipika R, Yu, Chen-Hsin, Mount, Stephen M, Moult, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480957/
https://www.ncbi.nlm.nih.gov/pubmed/26110739
http://dx.doi.org/10.1186/1471-2164-16-S8-S4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480957/
https://www.ncbi.nlm.nih.gov/pubmed/26110739
http://dx.doi.org/10.1186/1471-2164-16-S8-S4

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