Cargando…

Hemagglutinin Sequence Conservation Guided Stem Immunogen Design from Influenza A H3 Subtype

Seasonal epidemics caused by influenza A (H1 and H3 subtypes) and B viruses are a major global health threat. The traditional, trivalent influenza vaccines have limited efficacy because of rapid antigenic evolution of the circulating viruses. This antigenic variability mediates viral escape from the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mallajosyula, V. Vamsee Aditya, Citron, Michael, Ferrara, Francesca, Temperton, Nigel J., Liang, Xiaoping, Flynn, Jessica A., Varadarajan, Raghavan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481277/ https://www.ncbi.nlm.nih.gov/pubmed/26167164 http://dx.doi.org/10.3389/fimmu.2015.00329

Ejemplares similares

Protective efficacy of influenza group 2 hemagglutinin stem-fragment immunogen vaccines
por: Sutton, Troy C., et al.
Publicado: (2017)

Comparative Immunogenicity of Bacterially Expressed Soluble Trimers and Nanoparticle Displayed Influenza Hemagglutinin Stem Immunogens
por: Kar, Uddipan, et al.
Publicado: (2022)

Development of Lentiviral Vectors Pseudotyped With Influenza B Hemagglutinins: Application in Vaccine Immunogenicity, mAb Potency, and Sero-Surveillance Studies
por: Ferrara, Francesca, et al.
Publicado: (2021)

Stalking influenza by vaccination with pre-fusion headless HA mini-stem
por: Valkenburg, Sophie A., et al.
Publicado: (2016)

Analysis of the conserved protective epitopes of hemagglutinin on influenza A viruses
por: Jiao, Chenchen, et al.
Publicado: (2023)

Altering the Immunogenicity of Hemagglutinin Immunogens by Hyperglycosylation and Disulfide Stabilization
por: Thornlow, Dana N., et al.
Publicado: (2021)

Pseudotype-Based Neutralization Assays for Influenza: A Systematic Analysis
por: Carnell, George William, et al.
Publicado: (2015)

Isolation of a High Affinity Neutralizing Monoclonal Antibody against 2009 Pandemic H1N1 Virus That Binds at the ‘Sa’ Antigenic Site
por: Shembekar, Nachiket, et al.
Publicado: (2013)

Protective Efficacy of Recombinant Influenza Hemagglutinin Ectodomain Fusions
por: Mittal, Nidhi, et al.
Publicado: (2021)

Study of immunogenicity of recombinant proteins based on hemagglutinin and neuraminidase conservative epitopes of Influenza A virus
por: Dukhovlinov, Ilya, et al.
Publicado: (2013)

Insight into Highly Conserved H1 Subtype-Specific Epitopes in Influenza Virus Hemagglutinin
por: Cho, Ki Joon, et al.
Publicado: (2014)

Chimeric influenza haemagglutinins: Generation and use in pseudotype neutralization assays
por: Ferrara, Francesca, et al.
Publicado: (2016)

Enhanced Immunogenicity of Stabilized Trimeric Soluble Influenza Hemagglutinin
por: Weldon, William C., et al.
Publicado: (2010)

Correlation of Influenza B Haemagglutination Inhibiton, Single-Radial Haemolysis and Pseudotype-Based Microneutralisation Assays for Immunogenicity Testing of Seasonal Vaccines
por: Carnell, George W., et al.
Publicado: (2021)

Single Dose of Consensus Hemagglutinin-Based Virus-Like Particles Vaccine Protects Chickens against Divergent H5 Subtype Influenza Viruses
por: Wu, Peipei, et al.
Publicado: (2017)

Computational approach for predicting the conserved B-cell epitopes of hemagglutinin H7 subtype influenza virus
por: Wang, Xiangyu, et al.
Publicado: (2016)

The Length of N-Glycans of Recombinant H5N1 Hemagglutinin Influences the Oligomerization and Immunogenicity of Vaccine Antigen
por: Macioła, Agnieszka Katarzyna, et al.
Publicado: (2017)

Prime-Boost Vaccination With a Novel Hemagglutinin Protein Produced in Bacteria Induces Neutralizing Antibody Responses Against H5-Subtype Influenza Viruses in Commercial Chickens
por: Sączyńska, Violetta, et al.
Publicado: (2019)

Cross-Reactive and Lineage-Specific Single Domain Antibodies against Influenza B Hemagglutinin
por: Ramage, Walter, et al.
Publicado: (2019)

Protection against Multiple Subtypes of Influenza Viruses by Virus-Like Particle Vaccines Based on a Hemagglutinin Conserved Epitope
por: Chen, Shaoheng, et al.
Publicado: (2015)

Influenza Virus Vaccine Based on the Conserved Hemagglutinin Stalk Domain
por: Steel, John, et al.
Publicado: (2010)

Neutralizing Antibodies Targeting the Conserved Stem Region of Influenza Hemagglutinin
por: Nath Neerukonda, Sabari, et al.
Publicado: (2020)

Antiviral activity of stachyflin on influenza A viruses of different hemagglutinin subtypes
por: Motohashi, Yurie, et al.
Publicado: (2013)

Protective Efficacy of an Orf Virus-Vector Encoding the Hemagglutinin and the Nucleoprotein of Influenza A Virus in Swine
por: Joshi, Lok R., et al.
Publicado: (2021)

Immunogenicity and Clinical Efficacy of Influenza Vaccination in Pregnancy
por: Kay, Alexander W., et al.
Publicado: (2015)

Identification of a Highly Conserved H1 Subtype-Specific Epitope with Diagnostic Potential in the Hemagglutinin Protein of Influenza A Virus
por: Zhao, Rongmao, et al.
Publicado: (2011)

Diagnostic Potential of Recombinant scFv Antibodies Generated Against Hemagglutinin Protein of Influenza A Virus
por: Rajput, Roopali, et al.
Publicado: (2015)

Comparison of the Protective Efficacy of Neutralizing Epitopes of 2009 Pandemic H1N1 Influenza Hemagglutinin
por: Peng, Bo, et al.
Publicado: (2017)

Antibody recognition of an immunogenic influenza hemagglutinin-human leukocyte antigen class II complex
Publicado: (1991)

The Use of Hyperimmune Chicken Reference Sera Is Not Appropriate for the Validation of Influenza Pseudotype Neutralization Assays
por: Ferrara, Francesca, et al.
Publicado: (2017)

Subtype-specific structural constraints in the evolution of influenza A virus hemagglutinin genes
por: Gultyaev, Alexander P., et al.
Publicado: (2016)

Cross-Reactive Antibodies Binding to the Influenza Virus Subtype H11 Hemagglutinin
por: Strohmeier, Shirin, et al.
Publicado: (2019)

Hemagglutinin Subtype Specificity and Mechanisms of Highly Pathogenic Avian Influenza Virus Genesis
por: de Bruin, Anja C. M., et al.
Publicado: (2022)

Genetic characterization of a new candidate hemagglutinin subtype of influenza A viruses
por: Fereidouni, Sasan, et al.
Publicado: (2023)

Structural dynamics reveal subtype-specific activation and inhibition of influenza virus hemagglutinin
por: Garcia, Natalie K., et al.
Publicado: (2023)

The use of equine influenza pseudotypes for serological screening
por: Scott, Simon, et al.
Publicado: (2012)

Large-Scale Analysis of B-Cell Epitopes on Influenza Virus Hemagglutinin – Implications for Cross-Reactivity of Neutralizing Antibodies
por: Sun, Jing, et al.
Publicado: (2014)

Influenza Vaccination Results in Differential Hemagglutinin Stalk-Specific Fc-Mediated Functions in Individuals Living With or Without HIV
por: Motsoeneng, Boitumelo M., et al.
Publicado: (2022)

Nanobodies mapped to cross-reactive and divergent epitopes on A(H7N9) influenza hemagglutinin using yeast display
por: Gaiotto, Tiziano, et al.
Publicado: (2021)

Immunogenicity and Protective Potential of Mucosal Vaccine Formulations Based on Conserved Epitopes of Influenza A Viruses Fused to an Innovative Ring Nanoplatform in Mice and Chickens
por: Calzas, Cynthia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_56al2lk0nfcbcmu0jm3i466gti