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An Insulator Element Located at the Cyclin B1 Interacting Protein 1 Gene Locus Is Highly Conserved among Mammalian Species

Insulators are cis-elements that control the direction of enhancer and silencer activities (enhancer-blocking) and protect genes from silencing by heterochromatinization (barrier activity). Understanding insulators is critical to elucidate gene regulatory mechanisms at chromosomal domain levels. Her...

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Detalles Bibliográficos
Autores principales: Yoshida, Wataru, Tomikawa, Junko, Inaki, Makoto, Kimura, Hiroshi, Onodera, Masafumi, Hata, Kenichiro, Nakabayashi, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481373/
https://www.ncbi.nlm.nih.gov/pubmed/26110280
http://dx.doi.org/10.1371/journal.pone.0131204