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Computational Optimization of Bioanalytical Parameters for the Evaluation of the Toxicity of the Phytomarker 1,4 Napthoquinone and its Metabolite 1,2,4-trihydroxynapththalene
OBJECTIVES: Lawsone (1,4 naphthoquinone) is a non redox cycling compound that can be catalyzed by DT diaphorase (DTD) into 1,2,4-trihydroxynaphthalene (THN), which can generate reactive oxygen species by auto oxidation. The purpose of this study was to evaluate the toxicity of the phytomarker 1,4 na...
Autores principales: | Gopal, Velmani, AL Rashid, Mohammad Harun, Majumder, Sayani, Maiti, Partha Pratim, Mandal, Subhash C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KOREAN PHARMACOPUNCTURE INSTITUTE
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481394/ https://www.ncbi.nlm.nih.gov/pubmed/26120483 http://dx.doi.org/10.3831/KPI.2015.18.010 |
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