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Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism
Insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF1R) signalling is required for normal embryonic growth and development. Previous reports indicated that the IGF/IGF1R/MAPK pathway contributes to neural induction and the IGF/IGF1R/PI3K/Akt pathway to eye development. Here, we repor...
Autores principales: | Haramoto, Yoshikazu, Takahashi, Shuji, Oshima, Tomomi, Onuma, Yasuko, Ito, Yuzuru, Asashima, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481404/ https://www.ncbi.nlm.nih.gov/pubmed/26112133 http://dx.doi.org/10.1038/srep11603 |
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