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Notch intracellular domain overexpression in adipocytes confers lipodystrophy in mice

OBJECTIVE: The Notch family of intermembrane receptors is highly conserved across species and is involved in cell fate and lineage control. Previous in vitro studies have shown that Notch may inhibit adipogenesis. Here we describe the role of Notch in adipose tissue by employing an in vivo murine mo...

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Detalles Bibliográficos
Autores principales:	Chartoumpekis, Dionysios V., Palliyaguru, Dushani L., Wakabayashi, Nobunao, Khoo, Nicholas K.H., Schoiswohl, Gabriele, O'Doherty, Robert M., Kensler, Thomas W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481462/ https://www.ncbi.nlm.nih.gov/pubmed/26137442 http://dx.doi.org/10.1016/j.molmet.2015.04.004

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