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Effect of Variation in hemorheology between human and animal blood on the binding efficacy of vascular-targeted carriers
Animal models are extensively used to evaluate the in vivo functionality of novel drug delivery systems (DDS). However, many variations likely exist in vivo between the animals and human physiological environment that significantly alter results obtained with animal models relative to human system....
Autores principales: | Namdee, K., Carrasco-Teja, M., Fish, M. B., Charoenphol, P., Eniola-Adefeso, O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481524/ https://www.ncbi.nlm.nih.gov/pubmed/26113000 http://dx.doi.org/10.1038/srep11631 |
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