Targeting the CaMKII/ERK Interaction in the Heart Prevents Cardiac Hypertrophy

AIMS: Activation of Ca(2+)/Calmodulin protein kinase II (CaMKII) is an important step in signaling of cardiac hypertrophy. The molecular mechanisms by which CaMKII integrates with other pathways in the heart are incompletely understood. We hypothesize that CaMKII association with extracellular regul...

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Detalles Bibliográficos
Autores principales: Cipolletta, Ersilia, Rusciano, Maria Rosaria, Maione, Angela Serena, Santulli, Gaetano, Sorriento, Daniela, Del Giudice, Carmine, Ciccarelli, Michele, Franco, Antonietta, Crola, Catherine, Campiglia, Pietro, Sala, Marina, Gomez-Monterrey, Isabel, De Luca, Nicola, Trimarco, Bruno, Iaccarino, Guido, Illario, Maddalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481531/
https://www.ncbi.nlm.nih.gov/pubmed/26110816
http://dx.doi.org/10.1371/journal.pone.0130477

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