Cargando…
AKTIP/Ft1, a New Shelterin-Interacting Factor Required for Telomere Maintenance
Telomeres are nucleoprotein complexes that protect the ends of linear chromosomes from incomplete replication, degradation and detection as DNA breaks. Mammalian telomeres are protected by shelterin, a multiprotein complex that binds the TTAGGG telomeric repeats and recruits a series of additional f...
Autores principales: | Burla, Romina, Carcuro, Mariateresa, Raffa, Grazia D., Galati, Alessandra, Raimondo, Domenico, Rizzo, Angela, La Torre, Mattia, Micheli, Emanuela, Ciapponi, Laura, Cenci, Giovanni, Cundari, Enrico, Musio, Antonio, Biroccio, Annamaria, Cacchione, Stefano, Gatti, Maurizio, Saggio, Isabella |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481533/ https://www.ncbi.nlm.nih.gov/pubmed/26110528 http://dx.doi.org/10.1371/journal.pgen.1005167 |
Ejemplares similares
-
The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence
por: Burla, Romina, et al.
Publicado: (2016) -
The Analysis of Pendolino (peo) Mutants Reveals Differences in the Fusigenic Potential among Drosophila Telomeres
por: Cenci, Giovanni, et al.
Publicado: (2015) -
AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody
por: Merigliano, Chiara, et al.
Publicado: (2021) -
Combined alteration of lamin and nuclear morphology influences the localization of the tumor-associated factor AKTIP
por: La Torre, Mattia, et al.
Publicado: (2022) -
Mice with reduced expression of the telomere‐associated protein Ft1 develop p53‐sensitive progeroid traits
por: La Torre, Mattia, et al.
Publicado: (2018)