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Cobb syndrome: A rare cause of paraplegia
Cobb syndrome is an exceedingly rare clinical condition defined by the presence of a vascular skin nevus and an angioma in the spinal canal at the same metamere. We report the case of a 14-year-old boy who presented with sudden onset paraplegia. Physical examination showed port-wine stains over butt...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Indian Academy of Neurosciences
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481555/ https://www.ncbi.nlm.nih.gov/pubmed/26130930 http://dx.doi.org/10.5214/ans.0972.7531.220312 |
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author | Pal, Partha Ray, Sayantan Chakraborty, Sumit Dey, Subhasish Talukdar, Arunansu |
author_facet | Pal, Partha Ray, Sayantan Chakraborty, Sumit Dey, Subhasish Talukdar, Arunansu |
author_sort | Pal, Partha |
collection | PubMed |
description | Cobb syndrome is an exceedingly rare clinical condition defined by the presence of a vascular skin nevus and an angioma in the spinal canal at the same metamere. We report the case of a 14-year-old boy who presented with sudden onset paraplegia. Physical examination showed port-wine stains over buttock and thigh. Magnetic resonance (MR) angiogram of the dorso-lumbar spine revealed a large arteriovenous malformation (AVM) at D(11)-D(12) to L(2)-L(3) levels. These concurrent findings led to the diagnosis of Cobb’s syndrome. The patient received orally administered prednisolone therapy and underwent endovascular embolization of spinal angioma. Cobb’s syndrome is a rare disease entity and literature search revealed only a few case reports and series mentioning this condition to date. The importance lies in the recognition that cutaneous vascular lesions may clue to an associated spinal cord angioma or AVM that may lead to weakness or paralysis. |
format | Online Article Text |
id | pubmed-4481555 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Indian Academy of Neurosciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-44815552015-07-01 Cobb syndrome: A rare cause of paraplegia Pal, Partha Ray, Sayantan Chakraborty, Sumit Dey, Subhasish Talukdar, Arunansu Ann Neurosci Case Report Cobb syndrome is an exceedingly rare clinical condition defined by the presence of a vascular skin nevus and an angioma in the spinal canal at the same metamere. We report the case of a 14-year-old boy who presented with sudden onset paraplegia. Physical examination showed port-wine stains over buttock and thigh. Magnetic resonance (MR) angiogram of the dorso-lumbar spine revealed a large arteriovenous malformation (AVM) at D(11)-D(12) to L(2)-L(3) levels. These concurrent findings led to the diagnosis of Cobb’s syndrome. The patient received orally administered prednisolone therapy and underwent endovascular embolization of spinal angioma. Cobb’s syndrome is a rare disease entity and literature search revealed only a few case reports and series mentioning this condition to date. The importance lies in the recognition that cutaneous vascular lesions may clue to an associated spinal cord angioma or AVM that may lead to weakness or paralysis. Indian Academy of Neurosciences 2015-07 /pmc/articles/PMC4481555/ /pubmed/26130930 http://dx.doi.org/10.5214/ans.0972.7531.220312 Text en Copyright © 2015, The National Academy of Sciences http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Pal, Partha Ray, Sayantan Chakraborty, Sumit Dey, Subhasish Talukdar, Arunansu Cobb syndrome: A rare cause of paraplegia |
title | Cobb syndrome: A rare cause of paraplegia |
title_full | Cobb syndrome: A rare cause of paraplegia |
title_fullStr | Cobb syndrome: A rare cause of paraplegia |
title_full_unstemmed | Cobb syndrome: A rare cause of paraplegia |
title_short | Cobb syndrome: A rare cause of paraplegia |
title_sort | cobb syndrome: a rare cause of paraplegia |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481555/ https://www.ncbi.nlm.nih.gov/pubmed/26130930 http://dx.doi.org/10.5214/ans.0972.7531.220312 |
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