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Cobb syndrome: A rare cause of paraplegia

Cobb syndrome is an exceedingly rare clinical condition defined by the presence of a vascular skin nevus and an angioma in the spinal canal at the same metamere. We report the case of a 14-year-old boy who presented with sudden onset paraplegia. Physical examination showed port-wine stains over butt...

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Autores principales: Pal, Partha, Ray, Sayantan, Chakraborty, Sumit, Dey, Subhasish, Talukdar, Arunansu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Academy of Neurosciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481555/
https://www.ncbi.nlm.nih.gov/pubmed/26130930
http://dx.doi.org/10.5214/ans.0972.7531.220312
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author Pal, Partha
Ray, Sayantan
Chakraborty, Sumit
Dey, Subhasish
Talukdar, Arunansu
author_facet Pal, Partha
Ray, Sayantan
Chakraborty, Sumit
Dey, Subhasish
Talukdar, Arunansu
author_sort Pal, Partha
collection PubMed
description Cobb syndrome is an exceedingly rare clinical condition defined by the presence of a vascular skin nevus and an angioma in the spinal canal at the same metamere. We report the case of a 14-year-old boy who presented with sudden onset paraplegia. Physical examination showed port-wine stains over buttock and thigh. Magnetic resonance (MR) angiogram of the dorso-lumbar spine revealed a large arteriovenous malformation (AVM) at D(11)-D(12) to L(2)-L(3) levels. These concurrent findings led to the diagnosis of Cobb’s syndrome. The patient received orally administered prednisolone therapy and underwent endovascular embolization of spinal angioma. Cobb’s syndrome is a rare disease entity and literature search revealed only a few case reports and series mentioning this condition to date. The importance lies in the recognition that cutaneous vascular lesions may clue to an associated spinal cord angioma or AVM that may lead to weakness or paralysis.
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spelling pubmed-44815552015-07-01 Cobb syndrome: A rare cause of paraplegia Pal, Partha Ray, Sayantan Chakraborty, Sumit Dey, Subhasish Talukdar, Arunansu Ann Neurosci Case Report Cobb syndrome is an exceedingly rare clinical condition defined by the presence of a vascular skin nevus and an angioma in the spinal canal at the same metamere. We report the case of a 14-year-old boy who presented with sudden onset paraplegia. Physical examination showed port-wine stains over buttock and thigh. Magnetic resonance (MR) angiogram of the dorso-lumbar spine revealed a large arteriovenous malformation (AVM) at D(11)-D(12) to L(2)-L(3) levels. These concurrent findings led to the diagnosis of Cobb’s syndrome. The patient received orally administered prednisolone therapy and underwent endovascular embolization of spinal angioma. Cobb’s syndrome is a rare disease entity and literature search revealed only a few case reports and series mentioning this condition to date. The importance lies in the recognition that cutaneous vascular lesions may clue to an associated spinal cord angioma or AVM that may lead to weakness or paralysis. Indian Academy of Neurosciences 2015-07 /pmc/articles/PMC4481555/ /pubmed/26130930 http://dx.doi.org/10.5214/ans.0972.7531.220312 Text en Copyright © 2015, The National Academy of Sciences http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Pal, Partha
Ray, Sayantan
Chakraborty, Sumit
Dey, Subhasish
Talukdar, Arunansu
Cobb syndrome: A rare cause of paraplegia
title Cobb syndrome: A rare cause of paraplegia
title_full Cobb syndrome: A rare cause of paraplegia
title_fullStr Cobb syndrome: A rare cause of paraplegia
title_full_unstemmed Cobb syndrome: A rare cause of paraplegia
title_short Cobb syndrome: A rare cause of paraplegia
title_sort cobb syndrome: a rare cause of paraplegia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481555/
https://www.ncbi.nlm.nih.gov/pubmed/26130930
http://dx.doi.org/10.5214/ans.0972.7531.220312
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