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Clinically relevant enhancement of human sperm motility using compounds with reported phosphodiesterase inhibitor activity
STUDY QUESTION: Can we identify compound(s) with reported phosphodiesterase inhibitor (PDEI) activity that could be added to human spermatozoa in vitro to enhance their motility without compromising other sperm functions? SUMMARY ANSWER: We have identified several compounds that produce robust and e...
Autores principales: | Tardif, Steve, Madamidola, Oladipo A., Brown, Sean G., Frame, Lorna, Lefièvre, Linda, Wyatt, Paul G., Barratt, Christopher L.R., Martins Da Silva, Sarah J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481575/ https://www.ncbi.nlm.nih.gov/pubmed/25124668 http://dx.doi.org/10.1093/humrep/deu196 |
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