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Deep sequencing analysis of viral infection and evolution allows rapid and detailed characterization of viral mutant spectrum

Motivation: The study of RNA virus populations is a challenging task. Each population of RNA virus is composed of a collection of different, yet related genomes often referred to as mutant spectra or quasispecies. Virologists using deep sequencing technologies face major obstacles when studying viru...

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Detalles Bibliográficos
Autores principales: Isakov, Ofer, Bordería, Antonio V., Golan, David, Hamenahem, Amir, Celniker, Gershon, Yoffe, Liron, Blanc, Hervé, Vignuzzi, Marco, Shomron, Noam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481840/
https://www.ncbi.nlm.nih.gov/pubmed/25701575
http://dx.doi.org/10.1093/bioinformatics/btv101