Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference

OBJECTIVE: To conduct an epigenome-wide analysis of DNA methylation and obesity traits. DESIGN AND METHODS: We quantified DNA methylation in CD4+ T-cells using the Illumina Infinium Human Methylation450 array in 991 participants of the Genetics of Lipid Lowering Drugs and Diet Network. We modeled me...

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Detalles Bibliográficos
Autores principales: Aslibekyan, Stella, Demerath, Ellen W., Mendelson, Michael, Zhi, Degui, Guan, Weihua, Liang, Liming, Sha, Jin, Pankow, James S., Liu, Chunyu, Irvin, Marguerite R., Fornage, Myriam, Hidalgo, Bertha, Lin, Li-An, Thibeault, Krista Stanton, Bressler, Jan, Tsai, Michael Y., Grove, Megan L., Hopkins, Paul N., Boerwinkle, Eric, Borecki, Ingrid B., Ordovas, Jose M., Levy, Daniel, Tiwari, Hemant K., Absher, Devin M., Arnett, Donna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482015/
https://www.ncbi.nlm.nih.gov/pubmed/26110892
http://dx.doi.org/10.1002/oby.21111

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