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The immunomodulating V and W proteins of Nipah virus determine disease course

The viral determinants that contribute to Nipah virus (NiV)-mediated disease are poorly understood compared with other paramyxoviruses. Here we use recombinant NiVs (rNiVs) to examine the contributions of the NiV V and W proteins to NiV pathogenesis in a ferret model. We show that a V-deficient rNiV...

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Detalles Bibliográficos
Autores principales: Satterfield, Benjamin A., Cross, Robert W., Fenton, Karla A., Agans, Krystle N., Basler, Christopher F., Geisbert, Thomas W., Mire, Chad E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482017/
https://www.ncbi.nlm.nih.gov/pubmed/26105519
http://dx.doi.org/10.1038/ncomms8483