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The immunomodulating V and W proteins of Nipah virus determine disease course
The viral determinants that contribute to Nipah virus (NiV)-mediated disease are poorly understood compared with other paramyxoviruses. Here we use recombinant NiVs (rNiVs) to examine the contributions of the NiV V and W proteins to NiV pathogenesis in a ferret model. We show that a V-deficient rNiV...
Autores principales: | Satterfield, Benjamin A., Cross, Robert W., Fenton, Karla A., Agans, Krystle N., Basler, Christopher F., Geisbert, Thomas W., Mire, Chad E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482017/ https://www.ncbi.nlm.nih.gov/pubmed/26105519 http://dx.doi.org/10.1038/ncomms8483 |
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