AKT phosphorylates H3-threonine 45 to facilitate termination of gene transcription in response to DNA damage

Post-translational modifications of core histones affect various cellular processes, primarily through transcription. However, their relationship with the termination of transcription has remained largely unknown. In this study, we show that DNA damage-activated AKT phosphorylates threonine 45 of co...

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Detalles Bibliográficos
Autores principales: Lee, Jong-Hyuk, Kang, Byung-Hee, Jang, Hyonchol, Kim, Tae Wan, Choi, Jinmi, Kwak, Sojung, Han, Jungwon, Cho, Eun-Jung, Youn, Hong-Duk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482061/
https://www.ncbi.nlm.nih.gov/pubmed/25813038
http://dx.doi.org/10.1093/nar/gkv176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482061/
https://www.ncbi.nlm.nih.gov/pubmed/25813038
http://dx.doi.org/10.1093/nar/gkv176

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