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AKT phosphorylates H3-threonine 45 to facilitate termination of gene transcription in response to DNA damage
Post-translational modifications of core histones affect various cellular processes, primarily through transcription. However, their relationship with the termination of transcription has remained largely unknown. In this study, we show that DNA damage-activated AKT phosphorylates threonine 45 of co...
Autores principales: | Lee, Jong-Hyuk, Kang, Byung-Hee, Jang, Hyonchol, Kim, Tae Wan, Choi, Jinmi, Kwak, Sojung, Han, Jungwon, Cho, Eun-Jung, Youn, Hong-Duk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482061/ https://www.ncbi.nlm.nih.gov/pubmed/25813038 http://dx.doi.org/10.1093/nar/gkv176 |
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