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The HIV-1 Rev response element (RRE) adopts alternative conformations that promote different rates of virus replication

The HIV Rev protein forms a complex with a 351 nucleotide sequence present in unspliced and incompletely spliced human immunodeficiency virus (HIV) mRNAs, the Rev response element (RRE), to recruit the cellular nuclear export receptor Crm1 and Ran-GTP. This complex facilitates nucleo-cytoplasmic exp...

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Detalles Bibliográficos
Autores principales:	Sherpa, Chringma, Rausch, Jason W., Le Grice, Stuart F.J., Hammarskjold, Marie-Louise, Rekosh, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482075/ https://www.ncbi.nlm.nih.gov/pubmed/25855816 http://dx.doi.org/10.1093/nar/gkv313

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