Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold Morphogenesis

Skin disorders are widespread, but available treatments are limited. A more comprehensive understanding of skin development mechanisms will drive identification of new treatment targets and modalities. Here we report the Zebrafish Integument Project (ZIP), an expression-driven platform for identifyi...

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Detalles Bibliográficos
Autores principales: Westcot, Stephanie E., Hatzold, Julia, Urban, Mark D., Richetti, Stefânia K., Skuster, Kimberly J., Harm, Rhianna M., Lopez Cervera, Roberto, Umemoto, Noriko, McNulty, Melissa S., Clark, Karl J., Hammerschmidt, Matthias, Ekker, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482254/
https://www.ncbi.nlm.nih.gov/pubmed/26110643
http://dx.doi.org/10.1371/journal.pone.0130688

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