Cutaneous exposure to agglomerates of silica nanoparticles and allergen results in IgE-biased immune response and increased sensitivity to anaphylaxis in mice

BACKGROUND: The skin is a key route of human exposure to nanomaterials, which typically occurs simultaneously with exposure to other chemical and environmental allergen. However, little is known about the hazards of nanomaterial exposure via the skin, particularly when accompanied by exposure to oth...

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Detalles Bibliográficos
Autores principales: Hirai, Toshiro, Yoshioka, Yasuo, Takahashi, Hideki, Ichihashi, Ko-ichi, Udaka, Asako, Mori, Takahide, Nishijima, Nobuo, Yoshida, Tokuyuki, Nagano, Kazuya, Kamada, Haruhiko, Tsunoda, Shin-ichi, Takagi, Tatsuya, Ishii, Ken J., Nabeshi, Hiromi, Yoshikawa, Tomoaki, Higashisaka, Kazuma, Tsutsumi, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482284/
https://www.ncbi.nlm.nih.gov/pubmed/26113229
http://dx.doi.org/10.1186/s12989-015-0095-3

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