Development of a Bioluminescent Nitroreductase Probe for Preclinical Imaging

Bacterial nitroreductases (NTRs) have been widely utilized in the development of novel antibiotics, degradation of pollutants, and gene-directed enzyme prodrug therapy (GDEPT) of cancer that reached clinical trials. In case of GDEPT, since NTR is not naturally present in mammalian cells, the prodrug...

Descripción completa

Detalles Bibliográficos
Autores principales: Vorobyeva, Anzhelika G., Stanton, Michael, Godinat, Aurélien, Lund, Kjetil B., Karateev, Grigory G., Francis, Kevin P., Allen, Elizabeth, Gelovani, Juri G., McCormack, Emmet, Tangney, Mark, Dubikovskaya, Elena A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482324/
https://www.ncbi.nlm.nih.gov/pubmed/26110789
http://dx.doi.org/10.1371/journal.pone.0131037

Ejemplares similares

Ejemplares similares