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Histone demethylase LSD1-mediated repression of GATA-2 is critical for erythroid differentiation

BACKGROUND: The transcription factor GATA-2 is predominantly expressed in hematopoietic stem and progenitor cells and counteracts the erythroid-specific transcription factor GATA-1, to modulate the proliferation and differentiation of hematopoietic cells. During hematopoietic cell differentiation, G...

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Detalles Bibliográficos
Autores principales:	Guo, Yidi, Fu, Xueqi, Jin, Yue, Sun, Jing, Liu, Ye, Huo, Bo, Li, Xiang, Hu, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482369/ https://www.ncbi.nlm.nih.gov/pubmed/26124638 http://dx.doi.org/10.2147/DDDT.S81911

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