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Combination of erlotinib and a PARP inhibitor inhibits growth of A2780 tumor xenografts due to increased autophagy
BACKGROUND: Ovarian cancer is the leading cause of death in women with gynecological malignancy worldwide. Despite multiple new approaches to treatment, relapse remains almost inevitable in patients with advanced disease. The poor outcome of advanced ovarian cancer treated with conventional therapy...
Autores principales: | Sui, Hongying, Shi, Caixia, Yan, Zhipeng, Li, Hucheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482371/ https://www.ncbi.nlm.nih.gov/pubmed/26124641 http://dx.doi.org/10.2147/DDDT.S82035 |
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