Therapeutic effects of C-28 methyl ester of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO-Me; bardoxolone methyl) on radiation-induced lung inflammation and fibrosis in mice

The C-28 methyl ester of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO-Me), one of the synthetic triterpenoids, has been found to have potent anti-inflammatory and anticancer properties in vitro and in vivo. However, its usefulness in mitigating radiation-induced lung injury (RILI), including r...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yan-Yang, Zhang, Cui-Ying, Ma, Ya-Qiong, He, Zhi-Xu, Zhe, Hong, Zhou, Shu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482372/
https://www.ncbi.nlm.nih.gov/pubmed/26124639
http://dx.doi.org/10.2147/DDDT.S80958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482372/
https://www.ncbi.nlm.nih.gov/pubmed/26124639
http://dx.doi.org/10.2147/DDDT.S80958

Ejemplares similares