Characterization of renal biomarkers for use in clinical trials: effect of preanalytical processing and qualification using samples from subjects with diabetes

BACKGROUND: Identifying the potential for drug-induced kidney injury is essential for the successful research and development of new drugs. Newer and more sensitive preclinical drug-induced kidney injury biomarkers are now qualified for use in rat toxicology studies, but biomarkers for clinical stud...

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Detalles Bibliográficos
Autores principales: Brott, David A, Furlong, Stephen T, Adler, Scott H, Hainer, James W, Arani, Ramin B, Pinches, Mark, Rossing, Peter, Chaturvedi, Nish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482374/
https://www.ncbi.nlm.nih.gov/pubmed/26124642
http://dx.doi.org/10.2147/DDDT.S78792

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