Detection of epidermal growth factor receptor mutation in lung cancer by droplet digital polymerase chain reaction

BACKGROUND: Two types of epidermal growth factor receptor (EGFR) mutations in exon 19 and exon 21 (ex19del and L858R) are prevalent in lung cancer patients and sensitive to targeted EGFR inhibition. A resistance mutation in exon 20 (T790M) has been found to accompany drug treatment when patients rel...

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Detalles Bibliográficos
Autores principales: Xu, Qing, Zhu, Yazhen, Bai, Yali, Wei, Xiumin, Zheng, Xirun, Mao, Mao, Zheng, Guangjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482376/
https://www.ncbi.nlm.nih.gov/pubmed/26124670
http://dx.doi.org/10.2147/OTT.S84938

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