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Gamma scintigraphic study of the hydrodynamically balanced matrix tablets of Metformin HCl in rabbits
The purpose of this study is to evaluate the in vitro and in vivo performance of gastro-retentive matrix tablets having Metformin HCl as model drug and combination of natural polymers. A total of 16 formulations were prepared by a wet granulation method using xanthan, tamarind seed powder, tamarind...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482377/ https://www.ncbi.nlm.nih.gov/pubmed/26124637 http://dx.doi.org/10.2147/DDDT.S82935 |