TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility

Cellular migration and contractility are fundamental processes that are regulated by a variety of concerted mechanisms such as cytoskeleton rearrangements, focal adhesion turnover, and Ca(2+) oscillations. TRPM4 is a Ca(2+)-activated non-selective cationic channel (Ca(2+)-NSCC) that conducts monoval...

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Detalles Bibliográficos
Autores principales: Cáceres, Mónica, Ortiz, Liliana, Recabarren, Tatiana, Romero, Anibal, Colombo, Alicia, Leiva-Salcedo, Elías, Varela, Diego, Rivas, José, Silva, Ian, Morales, Diego, Campusano, Camilo, Almarza, Oscar, Simon, Felipe, Toledo, Hector, Park, Kang-Sik, Trimmer, James S., Cerda, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482413/
https://www.ncbi.nlm.nih.gov/pubmed/26110647
http://dx.doi.org/10.1371/journal.pone.0130540

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