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Instrumental Role of Helicobacter pylori γ-Glutamyl Transpeptidase in VacA-Dependent Vacuolation in Gastric Epithelial Cells

Helicobacter pylori causes cellular vacuolation in host cells, a cytotoxic event attributed to vacuolating cytotoxin (VacA) and the presence of permeant weak bases such as ammonia. We report here the role of γ-glutamyl transpeptidase (GGT), a constitutively expressed secretory enzyme of H. pylori, i...

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Detalles Bibliográficos
Autores principales:	Ling, Samantha Shi Min, Khoo, Lawrence Han Boon, Hwang, Le-Ann, Yeoh, Khay Guan, Ho, Bow
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482420/ https://www.ncbi.nlm.nih.gov/pubmed/26111186 http://dx.doi.org/10.1371/journal.pone.0131460

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