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A Novel Feedback Loop That Controls Bimodal Expression of Genetic Competence
Gene expression can be highly heterogeneous in isogenic cell populations. An extreme type of heterogeneity is the so-called bistable or bimodal expression, whereby a cell can differentiate into two alternative expression states. Stochastic fluctuations of protein levels, also referred to as noise, p...
Autores principales: | Gamba, Pamela, Jonker, Martijs J., Hamoen, Leendert W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482431/ https://www.ncbi.nlm.nih.gov/pubmed/26110430 http://dx.doi.org/10.1371/journal.pgen.1005047 |
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