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The Effect of Nrf2 Pathway Activation on Human Pancreatic Islet Cells

BACKGROUND: Pancreatic islets are known to contain low level of antioxidants that renders them vulnerable to oxidative stress. Nrf2 is the master regulator of numerous genes, encoding antioxidant, detoxifying, and cytoprotective molecules. Activation of Nrf2 pathway induces up-regulation of numerous...

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Detalles Bibliográficos
Autores principales:	Masuda, Yuichi, Vaziri, Nosratola D., Li, Shiri, Le, Aimee, Hajighasemi-Ossareh, Mohammad, Robles, Lourdes, Foster, Clarence E., Stamos, Michael J., Al-Abodullah, Ismail, Ricordi, Camillo, Ichii, Hirohito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482439/ https://www.ncbi.nlm.nih.gov/pubmed/26110640 http://dx.doi.org/10.1371/journal.pone.0131012

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