Flow Cytometric Immunobead Assay for Detection of BCR-ABL1 Fusion Proteins in Chronic Myleoid Leukemia: Comparison with FISH and PCR Techniques

Chronic Myeloid Leukemia (CML) is characterized by a balanced translocation juxtaposing the Abelson (ABL) and breakpoint cluster region (BCR) genes. The resulting BCR-ABL1 oncogene leads to increased proliferation and survival of leukemic cells. Successful treatment of CML has been accompanied by st...

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Detalles Bibliográficos
Autores principales: Recchia, Anna Grazia, Caruso, Nadia, Bossio, Sabrina, Pellicanò, Mariavaleria, De Stefano, Laura, Franzese, Stefania, Palummo, Angela, Abbadessa, Vincenzo, Lucia, Eugenio, Gentile, Massimo, Vigna, Ernesto, Caracciolo, Clementina, Agostino, Antolino, Galimberti, Sara, Levato, Luciano, Stagno, Fabio, Molica, Stefano, Martino, Bruno, Vigneri, Paolo, Di Raimondo, Francesco, Morabito, Fortunato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482505/
https://www.ncbi.nlm.nih.gov/pubmed/26111048
http://dx.doi.org/10.1371/journal.pone.0130360

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