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Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo
Notch signalling is a fundamental pathway that shapes the developing embryo and sustains adult tissues by direct communication between ligand and receptor molecules on adjacent cells. Among the ligands are two Delta paralogues, DLL1 and DLL4, that are conserved in mammals and share a similar structu...
Autores principales: | Preuße, Kristina, Tveriakhina, Lena, Schuster-Gossler, Karin, Gaspar, Cláudia, Rosa, Alexandra Isabel, Henrique, Domingos, Gossler, Achim, Stauber, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482573/ https://www.ncbi.nlm.nih.gov/pubmed/26114479 http://dx.doi.org/10.1371/journal.pgen.1005328 |
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