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Intramolecular ex vivo Fluorescence Resonance Energy Transfer (FRET) of Dihydropyridine Receptor (DHPR) β(1a) Subunit Reveals Conformational Change Induced by RYR1 in Mouse Skeletal Myotubes

The dihydropyridine receptor (DHPR) β(1a) subunit is essential for skeletal muscle excitation-contraction coupling, but the structural organization of β(1a) as part of the macromolecular DHPR-ryanodine receptor type I (RyR1) complex is still debatable. We used fluorescence resonance energy transfer...

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Detalles Bibliográficos
Autores principales:	Bhattacharya, Dipankar, Mehle, Andrew, Kamp, Timothy J., Balijepalli, Ravi C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482598/ https://www.ncbi.nlm.nih.gov/pubmed/26114725 http://dx.doi.org/10.1371/journal.pone.0131399

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