Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs

The filoviruses, which include the marburg- and ebolaviruses, have caused multiple outbreaks among humans this decade. Antibodies against the filovirus surface glycoprotein (GP) have been shown to provide life-saving therapy in nonhuman primates, but such antibodies are generally virus-specific. Man...

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Detalles Bibliográficos
Autores principales: Fusco, Marnie L., Hashiguchi, Takao, Cassan, Robyn, Biggins, Julia E., Murin, Charles D., Warfield, Kelly L., Li, Sheng, Holtsberg, Frederick W., Shulenin, Sergey, Vu, Hong, Olinger, Gene G., Kim, Do H., Whaley, Kevin J., Zeitlin, Larry, Ward, Andrew B., Nykiforuk, Cory, Aman, M. Javad, Berry, Jody, Saphire, Erica Ollmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482612/
https://www.ncbi.nlm.nih.gov/pubmed/26115029
http://dx.doi.org/10.1371/journal.ppat.1005016

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