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The UL13 and US3 Protein Kinases of Herpes Simplex Virus 1 Cooperate to Promote the Assembly and Release of Mature, Infectious Virions

Herpes simplex virus type 1 (HSV-1) encodes two bona fide serine/threonine protein kinases, the US3 and UL13 gene products. HSV-1 ΔUS3 mutants replicate with wild-type efficiency in cultured cells, and HSV-1 ΔUL13 mutants exhibit <10-fold reduction in infectious viral titers. Given these modest p...

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Detalles Bibliográficos
Autores principales:	Gershburg, Svetlana, Geltz, Joshua, Peterson, Karin E., Halford, William P., Gershburg, Edward
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482649/ https://www.ncbi.nlm.nih.gov/pubmed/26115119 http://dx.doi.org/10.1371/journal.pone.0131420

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