Oxidative Stress in Caenorhabditis elegans: Protective Effects of Spartin

Troyer syndrome is caused by a mutation in the SPG20 gene, which results in complete loss of expression of the protein spartin. We generated a genetic model of Troyer syndrome in worms to explore the locomotor consequences of a null mutation of the Caenorhabditis elegans SPG20 orthologue, F57B10.9,...

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Detalles Bibliográficos
Autores principales: Truong, Timothy, Karlinski, Zachary A., O’Hara, Christopher, Cabe, Maleen, Kim, Hongkyun, Bakowska, Joanna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482654/
https://www.ncbi.nlm.nih.gov/pubmed/26114733
http://dx.doi.org/10.1371/journal.pone.0130455

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