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PKC/ROS-Mediated NLRP3 Inflammasome Activation Is Attenuated by Leishmania Zinc-Metalloprotease during Infection

Parasites of the Leishmania genus infect and survive within macrophages by inhibiting several microbicidal molecules, such as nitric oxide and pro-inflammatory cytokines. In this context, various species of Leishmania have been reported to inhibit or reduce the production of IL-1β both in vitro and...

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Detalles Bibliográficos
Autores principales:	Shio, Marina Tiemi, Christian, Jan Gregor, Jung, Jee Yong, Chang, Kwang-Poo, Olivier, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482689/ https://www.ncbi.nlm.nih.gov/pubmed/26114647 http://dx.doi.org/10.1371/journal.pntd.0003868

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