Cargando…

Anterior Subcutaneous versus Submuscular Transposition of the Ulnar Nerve for Cubital Tunnel Syndrome: A Systematic Review and Meta-Analysis

OBJECTIVE: To pool reliable evidences for the optimum anterior transposition technique in the treatment of cubital tunnel syndrome by comparing the clinical efficacy of subcutaneous and submuscular anterior ulnar nerve transposition. METHODS: A comprehensive search was conducted in PubMed MEDLINE, C...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Chun-Hua, Chen, Chang-Xian, Xu, Jie, Wang, Han-Long, Ke, Xiao-Bin, Zhuang, Zhi-Yong, Lai, Zhan-Long, Wu, Zhi-Qiang, Lin, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482721/
https://www.ncbi.nlm.nih.gov/pubmed/26114865
http://dx.doi.org/10.1371/journal.pone.0130843
_version_ 1782378494437621760
author Liu, Chun-Hua
Chen, Chang-Xian
Xu, Jie
Wang, Han-Long
Ke, Xiao-Bin
Zhuang, Zhi-Yong
Lai, Zhan-Long
Wu, Zhi-Qiang
Lin, Qin
author_facet Liu, Chun-Hua
Chen, Chang-Xian
Xu, Jie
Wang, Han-Long
Ke, Xiao-Bin
Zhuang, Zhi-Yong
Lai, Zhan-Long
Wu, Zhi-Qiang
Lin, Qin
author_sort Liu, Chun-Hua
collection PubMed
description OBJECTIVE: To pool reliable evidences for the optimum anterior transposition technique in the treatment of cubital tunnel syndrome by comparing the clinical efficacy of subcutaneous and submuscular anterior ulnar nerve transposition. METHODS: A comprehensive search was conducted in PubMed MEDLINE, Cochrane Library, EMBASE, Web of Science, OVID AMED, EBSCO and potentially relevant surgical archives. Risk of bias of each included studies was evaluated according to Cochrane Handbook for Systematic Reviews of Interventions. The risk ratio (RR) and 95% confidence intervals (CI) were calculated for the clinical improvement in function compared to baseline. Heterogeneity was assessed across studies, and subgroup analysis was also performed based on the study type and follow-up duration. RESULTS: Three studies with a total of 352 participants were identified, and the clinically relevant improvement was used as the primary outcomes. Our meta-analysis revealed that no significant difference was observed between two comparison groups in terms of postoperative clinical improvement in those studies (RR 1.04, 95% CI 0.86 to 1.25, P = 0.72). Meanwhile, subgroup analyses by study type and follow-up duration revealed the consistent results with the overall estimate. Additionally, the pre- and postoperative motor nerve conduction velocities were reported in two studies with a total of 326 patients, but we could not perform a meta-analysis because of the lack of concrete numerical value in one study. The quality of evidence for clinical improvement was ‘low’ or ‘moderate’ on the basis of GRADE approach. CONCLUSIONS: Based on small numbers of studies with relatively poor methodological quality, the limited evidence is insufficient to identify the optimum anterior transposition technique in the treatment of cubital tunnel syndrome. The results of the present study suggest that anterior subcutaneous and submuscular transposition might be equally effective in patients with ulnar neuropathy at the elbow. Therefore, more high-quality randomized controlled trials with standardized clinical improvement metrics are required to further clarify this topic and to provide reproducible pre- and postoperative objective outcomes.
format Online
Article
Text
id pubmed-4482721
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-44827212015-06-29 Anterior Subcutaneous versus Submuscular Transposition of the Ulnar Nerve for Cubital Tunnel Syndrome: A Systematic Review and Meta-Analysis Liu, Chun-Hua Chen, Chang-Xian Xu, Jie Wang, Han-Long Ke, Xiao-Bin Zhuang, Zhi-Yong Lai, Zhan-Long Wu, Zhi-Qiang Lin, Qin PLoS One Research Article OBJECTIVE: To pool reliable evidences for the optimum anterior transposition technique in the treatment of cubital tunnel syndrome by comparing the clinical efficacy of subcutaneous and submuscular anterior ulnar nerve transposition. METHODS: A comprehensive search was conducted in PubMed MEDLINE, Cochrane Library, EMBASE, Web of Science, OVID AMED, EBSCO and potentially relevant surgical archives. Risk of bias of each included studies was evaluated according to Cochrane Handbook for Systematic Reviews of Interventions. The risk ratio (RR) and 95% confidence intervals (CI) were calculated for the clinical improvement in function compared to baseline. Heterogeneity was assessed across studies, and subgroup analysis was also performed based on the study type and follow-up duration. RESULTS: Three studies with a total of 352 participants were identified, and the clinically relevant improvement was used as the primary outcomes. Our meta-analysis revealed that no significant difference was observed between two comparison groups in terms of postoperative clinical improvement in those studies (RR 1.04, 95% CI 0.86 to 1.25, P = 0.72). Meanwhile, subgroup analyses by study type and follow-up duration revealed the consistent results with the overall estimate. Additionally, the pre- and postoperative motor nerve conduction velocities were reported in two studies with a total of 326 patients, but we could not perform a meta-analysis because of the lack of concrete numerical value in one study. The quality of evidence for clinical improvement was ‘low’ or ‘moderate’ on the basis of GRADE approach. CONCLUSIONS: Based on small numbers of studies with relatively poor methodological quality, the limited evidence is insufficient to identify the optimum anterior transposition technique in the treatment of cubital tunnel syndrome. The results of the present study suggest that anterior subcutaneous and submuscular transposition might be equally effective in patients with ulnar neuropathy at the elbow. Therefore, more high-quality randomized controlled trials with standardized clinical improvement metrics are required to further clarify this topic and to provide reproducible pre- and postoperative objective outcomes. Public Library of Science 2015-06-26 /pmc/articles/PMC4482721/ /pubmed/26114865 http://dx.doi.org/10.1371/journal.pone.0130843 Text en © 2015 Liu et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Liu, Chun-Hua
Chen, Chang-Xian
Xu, Jie
Wang, Han-Long
Ke, Xiao-Bin
Zhuang, Zhi-Yong
Lai, Zhan-Long
Wu, Zhi-Qiang
Lin, Qin
Anterior Subcutaneous versus Submuscular Transposition of the Ulnar Nerve for Cubital Tunnel Syndrome: A Systematic Review and Meta-Analysis
title Anterior Subcutaneous versus Submuscular Transposition of the Ulnar Nerve for Cubital Tunnel Syndrome: A Systematic Review and Meta-Analysis
title_full Anterior Subcutaneous versus Submuscular Transposition of the Ulnar Nerve for Cubital Tunnel Syndrome: A Systematic Review and Meta-Analysis
title_fullStr Anterior Subcutaneous versus Submuscular Transposition of the Ulnar Nerve for Cubital Tunnel Syndrome: A Systematic Review and Meta-Analysis
title_full_unstemmed Anterior Subcutaneous versus Submuscular Transposition of the Ulnar Nerve for Cubital Tunnel Syndrome: A Systematic Review and Meta-Analysis
title_short Anterior Subcutaneous versus Submuscular Transposition of the Ulnar Nerve for Cubital Tunnel Syndrome: A Systematic Review and Meta-Analysis
title_sort anterior subcutaneous versus submuscular transposition of the ulnar nerve for cubital tunnel syndrome: a systematic review and meta-analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482721/
https://www.ncbi.nlm.nih.gov/pubmed/26114865
http://dx.doi.org/10.1371/journal.pone.0130843
work_keys_str_mv AT liuchunhua anteriorsubcutaneousversussubmusculartranspositionoftheulnarnerveforcubitaltunnelsyndromeasystematicreviewandmetaanalysis
AT chenchangxian anteriorsubcutaneousversussubmusculartranspositionoftheulnarnerveforcubitaltunnelsyndromeasystematicreviewandmetaanalysis
AT xujie anteriorsubcutaneousversussubmusculartranspositionoftheulnarnerveforcubitaltunnelsyndromeasystematicreviewandmetaanalysis
AT wanghanlong anteriorsubcutaneousversussubmusculartranspositionoftheulnarnerveforcubitaltunnelsyndromeasystematicreviewandmetaanalysis
AT kexiaobin anteriorsubcutaneousversussubmusculartranspositionoftheulnarnerveforcubitaltunnelsyndromeasystematicreviewandmetaanalysis
AT zhuangzhiyong anteriorsubcutaneousversussubmusculartranspositionoftheulnarnerveforcubitaltunnelsyndromeasystematicreviewandmetaanalysis
AT laizhanlong anteriorsubcutaneousversussubmusculartranspositionoftheulnarnerveforcubitaltunnelsyndromeasystematicreviewandmetaanalysis
AT wuzhiqiang anteriorsubcutaneousversussubmusculartranspositionoftheulnarnerveforcubitaltunnelsyndromeasystematicreviewandmetaanalysis
AT linqin anteriorsubcutaneousversussubmusculartranspositionoftheulnarnerveforcubitaltunnelsyndromeasystematicreviewandmetaanalysis