Lipopolysaccharide-Induced CXCL10 mRNA Level and Six Stimulant-mRNA Combinations in Whole Blood: Novel Biomarkers for Bortezomib Responses Obtained from a Prospective Multicenter Trial for Patients with Multiple Myeloma

To identify predictive biomarkers for clinical responses to bortezomib treatment, 0.06 mL of each whole blood without any cell separation procedures was stimulated ex vivo using five agents, and eight mRNAs were quantified. In six centers, heparinized peripheral blood was prospectively obtained from...

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Detalles Bibliográficos
Autores principales: Watanabe, Takashi, Mitsuhashi, Masato, Sagawa, Morihiko, Ri, Masaki, Suzuki, Kenshi, Abe, Masahiro, Ohmachi, Ken, Nakagawa, Yasunori, Nakamura, Shingen, Chosa, Mizuki, Iida, Shinsuke, Kizaki, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482752/
https://www.ncbi.nlm.nih.gov/pubmed/26115406
http://dx.doi.org/10.1371/journal.pone.0128662

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