Pathogenicity of H5N8 virus in chickens from Korea in 2014

In 2014, two genetically distinct H5N8 highly pathogenic avian influenza (HPAI) viruses were isolated from poultry and wild birds in Korea. The intravenous pathogenicity indices for the two representative viruses were both 3.0. Mortality of chickens intranasally inoculated with the two H5N8 viruses...

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Autores principales: Song, Byung-Min, Kang, Hyun-Mi, Lee, Eun-Kyoung, Jeong, Jipseol, Kang, Yeojin, Lee, Hee-Soo, Lee, Youn-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2015
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483509/
https://www.ncbi.nlm.nih.gov/pubmed/25549219
http://dx.doi.org/10.4142/jvs.2015.16.2.237
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author Song, Byung-Min
Kang, Hyun-Mi
Lee, Eun-Kyoung
Jeong, Jipseol
Kang, Yeojin
Lee, Hee-Soo
Lee, Youn-Jeong
author_facet Song, Byung-Min
Kang, Hyun-Mi
Lee, Eun-Kyoung
Jeong, Jipseol
Kang, Yeojin
Lee, Hee-Soo
Lee, Youn-Jeong
author_sort Song, Byung-Min
collection PubMed
description In 2014, two genetically distinct H5N8 highly pathogenic avian influenza (HPAI) viruses were isolated from poultry and wild birds in Korea. The intravenous pathogenicity indices for the two representative viruses were both 3.0. Mortality of chickens intranasally inoculated with the two H5N8 viruses was 100% with a mean death times of 2.5 and 4.5 days. Mortality rates of the contact groups for the two H5N8 viruses were 33.3% and 66.6%. Our study showed that transmissibility of the novel H5N8 viruses was different from that of previously identified H5N1 HPAI viruses, possibly due to genetic changes.
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spelling pubmed-44835092015-06-29 Pathogenicity of H5N8 virus in chickens from Korea in 2014 Song, Byung-Min Kang, Hyun-Mi Lee, Eun-Kyoung Jeong, Jipseol Kang, Yeojin Lee, Hee-Soo Lee, Youn-Jeong J Vet Sci Short Communication In 2014, two genetically distinct H5N8 highly pathogenic avian influenza (HPAI) viruses were isolated from poultry and wild birds in Korea. The intravenous pathogenicity indices for the two representative viruses were both 3.0. Mortality of chickens intranasally inoculated with the two H5N8 viruses was 100% with a mean death times of 2.5 and 4.5 days. Mortality rates of the contact groups for the two H5N8 viruses were 33.3% and 66.6%. Our study showed that transmissibility of the novel H5N8 viruses was different from that of previously identified H5N1 HPAI viruses, possibly due to genetic changes. The Korean Society of Veterinary Science 2015-06 2015-06-17 /pmc/articles/PMC4483509/ /pubmed/25549219 http://dx.doi.org/10.4142/jvs.2015.16.2.237 Text en © 2015 The Korean Society of Veterinary Science. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Song, Byung-Min
Kang, Hyun-Mi
Lee, Eun-Kyoung
Jeong, Jipseol
Kang, Yeojin
Lee, Hee-Soo
Lee, Youn-Jeong
Pathogenicity of H5N8 virus in chickens from Korea in 2014
title Pathogenicity of H5N8 virus in chickens from Korea in 2014
title_full Pathogenicity of H5N8 virus in chickens from Korea in 2014
title_fullStr Pathogenicity of H5N8 virus in chickens from Korea in 2014
title_full_unstemmed Pathogenicity of H5N8 virus in chickens from Korea in 2014
title_short Pathogenicity of H5N8 virus in chickens from Korea in 2014
title_sort pathogenicity of h5n8 virus in chickens from korea in 2014
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483509/
https://www.ncbi.nlm.nih.gov/pubmed/25549219
http://dx.doi.org/10.4142/jvs.2015.16.2.237
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