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Intrapancreatic ectopic splenic tissue found in a cloned miniature pig
Somatic cell nuclear transfer (SCNT) is a cost-effective technique for producing transgenic pigs. However, abnormalities in the cloned pigs might prevent use these animals for clinical applications or disease modeling. In the present study, we generated several cloned pigs. One of the pigs was found...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Veterinary Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483510/ https://www.ncbi.nlm.nih.gov/pubmed/25643801 http://dx.doi.org/10.4142/jvs.2015.16.2.241 |
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author | Koo, Ok Jae Ha, Seung-Kwon Park, Sol Ji Park, Hee Jung Kim, Su Jin Kwon, Daekee Kang, Jung Taek Moon, Joon Ho Park, Eun Jung Jang, Goo Lee, Byeong Chun |
author_facet | Koo, Ok Jae Ha, Seung-Kwon Park, Sol Ji Park, Hee Jung Kim, Su Jin Kwon, Daekee Kang, Jung Taek Moon, Joon Ho Park, Eun Jung Jang, Goo Lee, Byeong Chun |
author_sort | Koo, Ok Jae |
collection | PubMed |
description | Somatic cell nuclear transfer (SCNT) is a cost-effective technique for producing transgenic pigs. However, abnormalities in the cloned pigs might prevent use these animals for clinical applications or disease modeling. In the present study, we generated several cloned pigs. One of the pigs was found to have intrapancreatic ectopic splenic tissue during histopathology analysis although this animal was grossly normal and genetically identical to the other cloned pigs. Ectopic splenic tissue in the pancreas is very rare, especially in animals. To the best of our knowledge, this is the first such report for cloned pigs. |
format | Online Article Text |
id | pubmed-4483510 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | The Korean Society of Veterinary Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-44835102015-06-29 Intrapancreatic ectopic splenic tissue found in a cloned miniature pig Koo, Ok Jae Ha, Seung-Kwon Park, Sol Ji Park, Hee Jung Kim, Su Jin Kwon, Daekee Kang, Jung Taek Moon, Joon Ho Park, Eun Jung Jang, Goo Lee, Byeong Chun J Vet Sci Case Report Somatic cell nuclear transfer (SCNT) is a cost-effective technique for producing transgenic pigs. However, abnormalities in the cloned pigs might prevent use these animals for clinical applications or disease modeling. In the present study, we generated several cloned pigs. One of the pigs was found to have intrapancreatic ectopic splenic tissue during histopathology analysis although this animal was grossly normal and genetically identical to the other cloned pigs. Ectopic splenic tissue in the pancreas is very rare, especially in animals. To the best of our knowledge, this is the first such report for cloned pigs. The Korean Society of Veterinary Science 2015-06 2015-06-17 /pmc/articles/PMC4483510/ /pubmed/25643801 http://dx.doi.org/10.4142/jvs.2015.16.2.241 Text en © 2015 The Korean Society of Veterinary Science. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Koo, Ok Jae Ha, Seung-Kwon Park, Sol Ji Park, Hee Jung Kim, Su Jin Kwon, Daekee Kang, Jung Taek Moon, Joon Ho Park, Eun Jung Jang, Goo Lee, Byeong Chun Intrapancreatic ectopic splenic tissue found in a cloned miniature pig |
title | Intrapancreatic ectopic splenic tissue found in a cloned miniature pig |
title_full | Intrapancreatic ectopic splenic tissue found in a cloned miniature pig |
title_fullStr | Intrapancreatic ectopic splenic tissue found in a cloned miniature pig |
title_full_unstemmed | Intrapancreatic ectopic splenic tissue found in a cloned miniature pig |
title_short | Intrapancreatic ectopic splenic tissue found in a cloned miniature pig |
title_sort | intrapancreatic ectopic splenic tissue found in a cloned miniature pig |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483510/ https://www.ncbi.nlm.nih.gov/pubmed/25643801 http://dx.doi.org/10.4142/jvs.2015.16.2.241 |
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