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Intrapancreatic ectopic splenic tissue found in a cloned miniature pig

Somatic cell nuclear transfer (SCNT) is a cost-effective technique for producing transgenic pigs. However, abnormalities in the cloned pigs might prevent use these animals for clinical applications or disease modeling. In the present study, we generated several cloned pigs. One of the pigs was found...

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Autores principales: Koo, Ok Jae, Ha, Seung-Kwon, Park, Sol Ji, Park, Hee Jung, Kim, Su Jin, Kwon, Daekee, Kang, Jung Taek, Moon, Joon Ho, Park, Eun Jung, Jang, Goo, Lee, Byeong Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483510/
https://www.ncbi.nlm.nih.gov/pubmed/25643801
http://dx.doi.org/10.4142/jvs.2015.16.2.241
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author Koo, Ok Jae
Ha, Seung-Kwon
Park, Sol Ji
Park, Hee Jung
Kim, Su Jin
Kwon, Daekee
Kang, Jung Taek
Moon, Joon Ho
Park, Eun Jung
Jang, Goo
Lee, Byeong Chun
author_facet Koo, Ok Jae
Ha, Seung-Kwon
Park, Sol Ji
Park, Hee Jung
Kim, Su Jin
Kwon, Daekee
Kang, Jung Taek
Moon, Joon Ho
Park, Eun Jung
Jang, Goo
Lee, Byeong Chun
author_sort Koo, Ok Jae
collection PubMed
description Somatic cell nuclear transfer (SCNT) is a cost-effective technique for producing transgenic pigs. However, abnormalities in the cloned pigs might prevent use these animals for clinical applications or disease modeling. In the present study, we generated several cloned pigs. One of the pigs was found to have intrapancreatic ectopic splenic tissue during histopathology analysis although this animal was grossly normal and genetically identical to the other cloned pigs. Ectopic splenic tissue in the pancreas is very rare, especially in animals. To the best of our knowledge, this is the first such report for cloned pigs.
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spelling pubmed-44835102015-06-29 Intrapancreatic ectopic splenic tissue found in a cloned miniature pig Koo, Ok Jae Ha, Seung-Kwon Park, Sol Ji Park, Hee Jung Kim, Su Jin Kwon, Daekee Kang, Jung Taek Moon, Joon Ho Park, Eun Jung Jang, Goo Lee, Byeong Chun J Vet Sci Case Report Somatic cell nuclear transfer (SCNT) is a cost-effective technique for producing transgenic pigs. However, abnormalities in the cloned pigs might prevent use these animals for clinical applications or disease modeling. In the present study, we generated several cloned pigs. One of the pigs was found to have intrapancreatic ectopic splenic tissue during histopathology analysis although this animal was grossly normal and genetically identical to the other cloned pigs. Ectopic splenic tissue in the pancreas is very rare, especially in animals. To the best of our knowledge, this is the first such report for cloned pigs. The Korean Society of Veterinary Science 2015-06 2015-06-17 /pmc/articles/PMC4483510/ /pubmed/25643801 http://dx.doi.org/10.4142/jvs.2015.16.2.241 Text en © 2015 The Korean Society of Veterinary Science. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Koo, Ok Jae
Ha, Seung-Kwon
Park, Sol Ji
Park, Hee Jung
Kim, Su Jin
Kwon, Daekee
Kang, Jung Taek
Moon, Joon Ho
Park, Eun Jung
Jang, Goo
Lee, Byeong Chun
Intrapancreatic ectopic splenic tissue found in a cloned miniature pig
title Intrapancreatic ectopic splenic tissue found in a cloned miniature pig
title_full Intrapancreatic ectopic splenic tissue found in a cloned miniature pig
title_fullStr Intrapancreatic ectopic splenic tissue found in a cloned miniature pig
title_full_unstemmed Intrapancreatic ectopic splenic tissue found in a cloned miniature pig
title_short Intrapancreatic ectopic splenic tissue found in a cloned miniature pig
title_sort intrapancreatic ectopic splenic tissue found in a cloned miniature pig
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483510/
https://www.ncbi.nlm.nih.gov/pubmed/25643801
http://dx.doi.org/10.4142/jvs.2015.16.2.241
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